Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with ...

Objective To test the hypothesis that postural instability with falling (PIF) and freezing of gait (FOG) are distinct subtypes of the postural instability/gait disturbance (PIGD) form of Parkinson's ...

Objective To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a large cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected from 901 patients ...

The nature of the neurological and mental disabilities resulting from severe head injuries are analysed in 150 patients. Mental handicap contributed more significantly to overall social disability ...

Departments of Neurology and Virology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA Correspondence to: Dr Harry Openshaw City of Hope National Medical Center, ...

Visual field loss was the presenting symptom in 19 patients with large intracranial aneurysms of the carotid system. Location of the aneurysm was cavernous, carotid-ophthalmic (two), supraclinoid ...

aDepartment of Ophthalmology, University of Alabama School of Medicine, 601 700 South 18th Street, Birmingham, Alabama, USA, bNeuro-ophthalmology Unit, University of California School of Medicine, San ...

Correspondence to Dr Michael A van Es, Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands; M.A.vanEs{at}umcutrecht.nl Objectives ...

Dr C C McIntyre, Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Ave ND20, Cleveland, OH 44195, USA; mcintyc{at}ccf.org Objective: Despite the clinical success of deep ...

Background Early fast-acting treatment (EFT) is the aggressive use of fast-acting therapies such as plasmapheresis, intravenous immunoglobulin and/or intravenous high-dose methylprednisolone (IVMP) ...

Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor ...

Department of Neurology, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland Correspondence to Dr Tuula Pirttilä, Department of Neurology, Bldg 5, Kuopio University Hospital POB ...