San Francisco and Arizona are in separate stages of quarterback drama as they prepare to conclude their season series Sunday ...

Big game coming for Aaron Rodgers? Matchup questions for the Seahawks and Rams? An edge for Jared Goff against the Eagles?

The San Francisco 49ers' defense took a new hit with the news that corner Deommodore Lenoir suffered an injury in Thursday's ...

The 49ers have the worst pass rush in the NFL by many measures, but Robert Saleh is hopeful they will improve.

Matt Maiocco highlights five key 49ers to keep an eye on in San Francisco's pivotal Week 11 matchup against the Arizona Cardinals on Sunday.

JJ McCarthy has shown the mercuriality of a rookie: One week he leads a gutsy win over the Lions, and the next he falls apart ...

The San Francisco 49ers will have a much-needed boost to their offense in Week 11 as quarterback Brock Purdy and wide ...

San Francisco 49ers offensive lineman Dominick Puni joined "You've Got Mail" presented by Delta Dental to discuss his Midwest upbringing, family of athletes, college journey, locker room traditions, ...

The Los Angeles Rams, led by 17th-year quarterback Matthew Stafford, have been absolutely dominant as of late. They have now ...

The San Francisco 49ers are starting to get healthier on offense with Ricky Pearsall preparing to return, but when he does, ...

San Francisco 49ers players visited a local children's hospital to spread cheer and lift the spirits of patients and their ...

Bosa was spotted by KPIX-TV reporter Matt Lively in the tunnel at Levi’s Stadium on Sunday, arriving to watch the 49ers ...