San Francisco and Arizona are in separate stages of quarterback drama as they prepare to conclude their season series Sunday ...

This time, the player was No. 1 cornerback Deommodore Lenoir. He injured his calf while jogging during Thursday's practice, according to head coach Kyle Shanahan. Lenoir is listed as questionable for ...

The San Francisco 49ers' defense took a new hit with the news that corner Deommodore Lenoir suffered an injury in Thursday's ...

The 49ers have the worst pass rush in the NFL by many measures, but Robert Saleh is hopeful they will improve.

The latest edition of Newsweek Sports Betting 📩 breaks down Seahawks-Rams, which headlines a massive Week 11 slate.

Matt Maiocco highlights five key 49ers to keep an eye on in San Francisco's pivotal Week 11 matchup against the Arizona Cardinals on Sunday.

The Seahawks and Rams have a pair of the league's most explosive playmakers, but here's why Sunday's game might be determined ...

JJ McCarthy has shown the mercuriality of a rookie: One week he leads a gutsy win over the Lions, and the next he falls apart ...

The San Francisco 49ers will have a much-needed boost to their offense in Week 11 as quarterback Brock Purdy and wide ...

San Francisco 49ers offensive lineman Dominick Puni joined "You've Got Mail" presented by Delta Dental to discuss his Midwest upbringing, family of athletes, college journey, locker room traditions, ...

The Los Angeles Rams, led by 17th-year quarterback Matthew Stafford, have been absolutely dominant as of late. They have now ...

The San Francisco 49ers are starting to get healthier on offense with Ricky Pearsall preparing to return, but when he does, ...