Arialys Therapeutics' precision medicine has shown preclinical potential to address the underlying cause of anti-NMDA ...

c-Fos in Alzheimer’s Disease In AD, c-Fos expression is aberrantly elevated, correlating with amyloid-β (Aβ) accumulation and cognitive impairment. Aβ stabilizes c-Fos via O-GlcNAcylation ...

Alzheimer's disease, the most common cause of dementia, is a neurodegenerative condition that can start developing 20 years before symptoms appear. It is the seventh leading cause of death in the U.S.

Dementia is a loss of brain function that affects memory, thinking, judgment, behavior, and language. Alzheimer's disease is the most common type of dementia. While there's no cure for dementia, ...

While there’s no cure for early onset Alzheimer’s disease, medications and supportive therapies can help manage symptoms related to memory loss, cognitive decline, and functional impairment ...

Alzheimer’s disease (AD) is the most common form of dementia, affecting approximately 7 million people in the United States. 1 Agitation is reported in up to 70% of patients with AD and is ...

NEW YORK, March 03, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders ...

One Phase 3 test of Auvelity met its main goal in Alzheimer’s agitation while the drug’s other pivotal trial showed numerical improvement that fell short of statistical significance. Axsome ...

However, in Alzheimer’s disease, tau undergoes pathogenic alterations, such as hyperphosphorylation, resulting in neurofibrillary tangles.⁷⁻⁸ Alzheimer Disease Acetylcholinesterase Inhibitors and an ...

NMDA (short for N-methyl-D-aspartate) receptor antagonists are a class of drugs that may help treat Alzheimer's disease, which causes memory loss, brain damage, and, eventually, death.There's no ...

In this study, recently published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, the authors investigated NMDA receptors due to their importance in synaptic transmission ...