Diagnosing and treating Crohn’s disease as early as possible can help prevent or stave off serious complications like perianal Crohn’s disease and colon cancer.

PALI-2108 is the first and only PDE4 inhibitor in development designed for targeted delivery to the terminal ileum and colon, addressing ...

In patients with Crohn’s disease (CD) who were in endoscopic remission, achieving intestinal ultrasound (IUS) transmural healing was associated with decreased risks for CD relapse, hospitalization, ...

Colorectal cancer — which includes cancer of the colon and of the rectum — is considered early onset when diagnosed in people under the age of 50. While the majority of diagnoses are still among ...

Background Intestinal fibrosis, a hallmark complication of Crohn’s disease (CD), frequently progresses to stricture formation and surgical intervention. Fibroblast metabolic reprogramming is important ...

What Is Crohn’s Constipation? You likely have constipation if it's hard for you to poop and you're having fewer bowel movements than you normally do. The same is true whether or not you have Crohn’s ...

The three-dimensional (3D) reconstruction of bowel strictures in Crohn’s disease can enhance patient understanding and facilitate multidisciplinary decision-making, offering a promising tool in ...

Intestinal fibrosis is a common and serious complication of inflammatory bowel diseases, often leading to strictures that require endoscopic or surgical intervention. Despite advances in ...

Background: Reliable predictors of surgical risk in Crohn’s disease (CD) with small bowel stenosis are lacking. Longitudinal CT enterography (CTE) derived body composition parameters may improve risk ...