Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) have become a critical global public health challenge due to their high resistance to β-lactam antibiotics and association with severe ...
aCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA bCritical Care Medicine Branch, National Heart Lung and Blood Institute, Bethesda, MD, USA ...
ABSTRACT: Antimicrobial resistance (AMR) is one of the top 10 threats to global health and it is estimated around 10 millions of deaths per year are associated with AMR until 2050. Burkina Faso is ...
ABSTRACT: Introduction: The misuse of antibiotics has driven the emergence of antimicrobial resistance, with certain bacterial species, including Klebsiella pneumoniae, initially susceptible to most ...
Abstract: The pathogenic drug resistant extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is becoming a global health concern. Prevalence of drug resistant extended-spectrum β-lactamase ...
Please provide your email address to receive an email when new articles are posted on . Carbapenems were prescribed as targeted therapy in 58.3% of all infections. Highlighting patient populations ...
Entasis Therapeutics, a clinical-stage biopharmaceutical company focused on the discovery and development of novel antibacterial products, today announced initiation of a Phase 1 clinical trial of its ...
1 Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, United States 2 Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, ...
Objectives: AmpC β-lactamases are classified as Amber Class C and Bush Group 1. AmpC β-lactamases can hydrolyze broad and extended-spectrum cephalosporins, and are not inhibited by β-lactamase ...
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