Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) have become a critical global public health challenge due to their high resistance to β-lactam antibiotics and association with severe ...

Mortality was strongly associated with older age, comorbidities, and infection type, underscoring the need for early and diagnosis-specific antimicrobial intervention.

Hareza DA, Bergman Y, Jacobs E, Mathers AJ, Hauser AR, Cosgrove SE, Simner PJ, Tamma PD. Establishing the Optimal Ceftriaxone MIC for Predicting ESBL Production in Bloodstream Infections. Open Forum ...

The production of extended-spectrum beta-lactamases (ESBL) is considered one of the most important resistance mechanisms that impair antimicrobial treatment of infections caused by Enterobacteriaceae.

1 Department of Medical Microbiology and Parasitology, David Umahi Federal Teaching Hospital, Uburu, Nigeria. 2 Department of Family Medicine, Alex-Ekwueme Federal University Teaching Hospital, ...

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Following colonization with antimicrobial-resistant pathogens, the risk for infection with the same pathogen remains increased for up to 2 years. There is a high overall rate of infection following ...

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Credit: Getty Images Researchers assessed patients with uncomplicated urinary tract infections to determine factors associated with extended-spectrum β-lactamase-producing uropathogens.