SUBACUTE inclusion-body encephalitis (Dawson) and subacute sclerosing leukoencephalitis (Van Bogaert) are now generally considered to be the same entity 1 characterized by inflammatory changes in the ...
The ultrastructural morphology of eosinophil cytolysis and extracellular trap cell death (ETosis) has predominantly been examined in non-neoplastic eosinophil-associated diseases, with a limited ...
SMA pathology affects a wider range of cells, including astrocytes and microglia, beyond alpha motor neurons. Advanced techniques revealed significant ventral horn neuron loss and abnormal morphology ...
INFANTILE progressive spinal muscular atrophy (Werdnig–Hoffmann syndrome) has been reported as occurring in 7 pairs of twins. 1–6 In only 4 of these cases were the twins thought to be monozygotic in ...
Neuronal intranuclear inclusion disease (NIID), a neurodegenerative disease previously thought to be rare, is increasingly recognized despite heterogeneous clinical presentations. NIID is ...
This manuscript describes important insight into the molecular mechanism by which destabilized mitochondrial proteins 'clog' import channels and contribute to the pathologic mitochondrial and cellular ...
1 Department of Pathology, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany 2 Institute for Biometry, Epidemiology and Information Processing, University of Veterinary ...
State Key Laboratory of Functions and Applications of Medicinal Plants/ Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, Guizhou 550004, China Engineering ...
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California 92093-0021, United States Biomedical Sciences Graduate Program, University of ...
We have made the discovery that pathological tau functions through the histone demethylase LSD1 in the Alzheimer’s disease pathway. Thus, we have identified a mechanism that links tau to the ...
From time to time we respond directly to reader comments or e-mails in an article, when it seems that doing so would be a useful teachable moment. One of the strengths of social media is that it is ...
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