The 49ers don't know for sure when wide receiver Brandon Aiyuk will be ready to return from last season's knee injury.

San Francisco 49ers wide receiver Brandon Aiyuk hasn't played since Oct. 20 because of a significant knee injury that limited ...

It's becoming more and more likely that the San Francisco 49ers could be without one of their top playmakers when the regular ...

The San Francisco 49ers do not expect to have receiver Brandon Aiyuk on the field for the season-opening game against the ...

The 49ers' wide receiver room is a mess. Injuries to key players like Brandon Aiyuk and Ricky Pearsall have left the wideout ...

49ers receiver Brandon Aiyuk continues to rehab from tearing his ACL and MCL in October of last season. With Aiyuk still on ...

San Francisco head coach Kyle Shanahan said Monday that Week 6 could be a realistic target for Aiyuk (ACL) to take the field, Vic Tafur of The Athletic reports. Shanahan pre-empted the estimate by ...

Levi’s Stadium welcomed a familiar face on Sunday as Rochelle Searight, the wife of San Francisco 49ers wide receiver Brandon ...

A few fantasy football stars and other potentially relevant players were dealing with injuries over the past NFL offseason.

When the 49ers offense is healthy, it's one of the best in the NFL. Unfortunately, their offense wasn't healthy last year, and it isn't healthy now.

Head coach Kyle Shanahan told reporters at a Monday press conference that fourth-round pick Jordan Watkins has a high-ankle sprain. Watkins is expected to miss about a month as a result of the injury.