The sequence distilled a 7-1 loss for the Astros and a four-game sweep at the hands of the A’s, the last-place team in the AL West. Houston mustered seven runs over four games against the A’s at Daikin Park, shrinking its division lead and highlighting the short-handed state of its lineup.

Part of why Houston struggled against the Athletics is health, as shortstop Jeremy Peña (rib) and third baseman Isaac Paredes (hamstring) are both on the 10-day IL. Peña leads the team with a .322 batting average, which also ranks third in baseball. Meanwhile, Paredes tops the squad with 19 homers.

The Astros capped another week of variance on Sunday by losing the finale of a four-game series against the Athletics 7-1, which sent Houston to its ninth loss in its last 10 home games.

After going 4-2 on the road after the All-Star break, the Astros have lost three in a row at home to the last-place A's.

The Minnesota Twins are set to be sellers at the trade deadline and the Houston Astros are interested in Willi Castro.

Preview the July 27 matchup between the Houston Astros and Athletics with odds over/under, game spread, betting lines and more.

BOTTOM LINE: The Athletics hit the road against the Houston Astros looking to continue a three-game road winning streak. Houston has a 33-22 record in home games and a 60-45 record overall. The Astros have the fourth-ranked team on-base percentage in the AL at .322.

The Houston Astros have done a wonderful job of overcoming some legitimate hurdles during the 2025 MLB regular season to find the amount of success that they ha