The treatment landscape for systemic lupus erythematosus (SLE) has shifted greatly in recent years, driven by the emergence of cell-based immunotherapies targeting pathogenic B-cell populations. Among ...

This study provides valuable insights into the role of the NF-kB and IKK signaling pathways in γδ T cell development and survival, using robust genetic mouse models. While the research is ...

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI)—designated Comprehensive Cancer ...

A team at Kyoto University's Center for iPS Cell Research and Application, or CiRA, has succeeded in creating component cells for the thymus using human induced pluripotent stem cells. The thymus ...

Once thought to be a flaw in the system, new research suggests that CD4 T cells may actually hold the key to maintaining a ...

A Human Immune Health Atlas, mapping 71 different immune cells and their changes over time, was released to support studies into the aging immune system.

Ben-Gurion University of the Negev's Prof. Alon Monsonego had discovered that T helper lymphocytes, a subset of immune cells which regulate immunity, undergo functional changes with age. These changes ...

Scientists at Ben-Gurion University of the Negev reported Wednesday, Oct. 29, 2025, that they have identified a subset of CD4 T helper cells that expands with age and appears to hunt down senescent ...

Using just one formula, you can create an entire table, generate a filtered view, calculate a running total, or build a ...

Regeneron has given up on a CAR-T candidate acquired from 2seventy bio last year, before it entered the second part of a phase 1/2 lymphoma study. The dual-targeting CAR-T, dubbed bbT369, was being ...

The tumor microenvironment (TME) comprises non-cancerous cells, extracellular matrix, and signaling molecules that interact with tumor cells. These dynamic interactions critically influence tumor ...