Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

The APT-Sepsis program significantly reduced infection-related outcomes in maternal care, demonstrating the impact of ...

The trial assessed APT-Sepsis implementation in 59 hospitals across Malawi and Uganda, involving a staggering 431,394 women ...

The sepsis market is constrained by a limited number of approved treatments and a high unmet need. However, the launch of ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial ...

Mouse and human data suggest endothelial ALOX15 and its lipids may help turn some lung clots into protection in sepsis lung injury, highlighting future therapeutic opportunities.

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

The scientists have discovered that a single inherited mutation causes whole-body issues in a model of inherited primary mitochondrial disorders after the immune response is sparked into action.

The Western Trust has been criticised after a Fermanagh patient was forced to wait in Altnagelvin Hospital’s emergency ...

Tumors trigger T-cell exhaustion through a TSP-1–CD47 signaling pathway. Blocking it can restore immune strength and improve cancer treatment.

The test was piloted and implemented in Manchester and has now been successfully introduced by NHS Greater Glasgow and Clyde ...