Researchers were able to restore the function of neurons linked to cognitive function and information processing in mice that ...

Cells have surface receptors that couple with proteins and other molecules to initiate or inhibit certain behaviors. Typically, the number of these receptors increases as the cell matures, but ...

The dopaminergic system has key roles in human physiology and is implicated in a broad range of neurological and neuropsychiatric conditions that are increasingly investigated using induced ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

Dopaminergic neurons arise from progenitor cells in the ventral midbrain under the coordinated influence of morphogens such as Sonic Hedgehog, Wnt and FGF, and the action of transcription factors ...

UCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical window of prenatal brain development, finding that the condition alters the ...

The signaling mechanisms underlying the transition from stem cells to olfactory neurons has been described. Cellular differentiation of stem cells into specialized cells requires many steps, including ...