NMDA (short for N-methyl-D-aspartate) receptor antagonists are a class of drugs that may help treat Alzheimer's disease, which causes memory loss, brain damage, and, eventually, death.There's no ...

More information: Sergio Escamilla et al, Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients, Alzheimer's & Dementia (2024). DOI: 10.1002/alz.14125 ...

In this study, recently published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, the authors investigated NMDA receptors due to their importance in synaptic transmission ...

Innovative protocol maps NMDA receptors in Alzheimer's-Affected brains. Universidad Miguel Hernandez de Elche. Funder Fondo de Investigaciones Sanitarias, Direcció General de Ciència i ...

A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for ...

One Phase 3 test of Auvelity met its main goal in Alzheimer’s agitation while the drug’s other pivotal trial showed numerical improvement that fell short of statistical significance. Axsome ...

NMDA receptor antagonists, like memantine (Namenda), help manage Alzheimer’s by controlling glutamate activity in the brain. This protects brain cells from too much stimulation. Memantine can ...

NMDA receptor antagonists work by regulating the activity of glutamate, another neurotransmitter that can be overactive in Alzheimer’s disease. This helps prevent excessive neuronal damage and ...

More information: Sergio Escamilla et al, Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients, Alzheimer's & Dementia (2024). DOI: 10.1002/alz.14125 ...