A new Vitrobot-based protocol produces graphene oxide cryo-EM grids with 55 percent average coverage and supports apoferritin ...

The meteoric rise of cryo-electron microscopy from an obscure imaging technique to a powerhouse for determining biomolecular structures is transforming our understanding of biology. Our knowledge of ...

A new review explains how cryo-FIB-SEM sits at the center of the cryo-electron tomography workflow, from vitrification and ...

This approach bypasses time-consuming protein purification steps, thereby reducing the number of crystals (ideally to one) required compared with X-ray diffraction methods. The range of applicable ...

Back in 2008, the California NanoSystems Institute at UCLA, or CNSI, debuted a one-of-a-kind resource for understanding biology at the smallest scales — a state-of-the-art cryo-electron microscope. By ...

From paints and inks to catalysts and drug-delivery materials, many advanced technologies rely on substances dispersed in organic solvents. Yet directly observing these materials in their native ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Could you start by explaining your background in crystallography and how you began using the Rigaku Synergy-ED system? Fraser: I began my journey into crystallography at the University of Edinburgh in ...

Radiation damage remains the principal limitation in achieving higher resolution in cryo-electron microscopy (cryo-EM), despite advances in cryoprotection and low-dose imaging. Researchers have ...

Cryo-stage with single axis holder for better stability and drift performance Symmetrical constant power C-TWIN image aberrations and lens design for minimizing lens hysteresis during mode switching ...

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