BMJ17h
Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis
OBJECTIVE To assess the feasibility of a new technique based on diffusion anisotropy to segment white and grey matter of the brain. To use this technique to measure the mean diffusivity (DÌ„) and ...
BMJ1d
Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
Objective To test the hypothesis that postural instability with falling (PIF) and freezing of gait (FOG) are distinct subtypes of the postural instability/gait disturbance (PIGD) form of Parkinson's ...
BMJ2d
Effectiveness of early cycles of fast-acting treatment in generalised myasthenia gravis
Background Early fast-acting treatment (EFT) is the aggressive use of fast-acting therapies such as plasmapheresis, intravenous immunoglobulin and/or intravenous high-dose methylprednisolone (IVMP) ...
BMJ13d
Silent progression of brain atrophy in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder
Correspondence to Dr Masahiro Mori, Neurology, Chiba University Graduate School of Medicine School of Medicine, Chiba, Chiba, Japan; morim{at}faculty.chiba-u.jp Objective To investigate longitudinal ...
BMJ3d
Corticosteroids in herpes simplex virus encephalitis
Departments of Neurology and Virology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA Correspondence to: Dr Harry Openshaw City of Hope National Medical Center, ...
BMJ11d
Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study
Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS). Methods 373 patients with ALS (El Escorial definite ...
BMJ12d
Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis
Objective To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a large cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected from 901 patients ...
BMJ4d
The Tolosa-Hunt syndrome
aDepartment of Ophthalmology, University of Alabama School of Medicine, 601 700 South 18th Street, Birmingham, Alabama, USA, bNeuro-ophthalmology Unit, University of California School of Medicine, San ...
BMJ2d
N18 in median somatosensory evoked potentials: a new indicator of medullary function useful for the diagnosis of brain death
Dr Masahiro Sonoo, Department of Neurology, Teikyo University School of Medicine, Kaga 2–11–1, Itabashi-ku, Tokyo 173, Japan. Telephone 0081 3 3964 1211 ext 1911; fax 0081 3 3964 6397; email sonoom{at ...
BMJ9d
Disability after severe head injury: observations on the use of the Glasgow Outcome Scale.
The nature of the neurological and mental disabilities resulting from severe head injuries are analysed in 150 patients. Mental handicap contributed more significantly to overall social disability ...
BMJ2d
Prognostication and contemporary management of clinically isolated syndrome
Clinically isolated syndrome (CIS) patients present with a single attack of inflammatory demyelination of the central nervous system. Recent advances in multiple sclerosis (MS) diagnostic criteria ...
BMJ12d
Data-driven evolution of neurosurgical gene therapy delivery in Parkinson’s disease
Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor ...