A new review maps how gut microbes and their metabolites bidirectionally shape T cell immunity to drive autoimmune, ...

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the immune system: the protein molecule TRAT1 (T Cell Receptor Associated ...

Cytokine signaling underlies the differentiation, activation and function of T helper (Th) cells, which orchestrate adaptive immunity. Naïve CD4+ T cells adopt specialised fates—Th1, Th2, Th17 or ...

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers headed by a team at The Ohio State University College of Medicine have shown how ...

A new review argues that periodontitis is driven less by bacteria than by the plasticity and instability of CD4+ T helper cells, whose conversion into hybrid IL-17-producing states fuels inflammatory ...