Scientists have created the first comprehensive map of DNA quadruplexes, fleeting knot-like structures that play an outsized ...

An international team, including researchers from HSE University, has created the first comprehensive map of ...

Like the aglets at the end of your shoelaces, protein-and-DNA assemblies known as telomeres protect the ends of your chromosomes from fraying. In work with potential implications for the development ...

This image is based on an x-ray crystal structure of a G-quadruplex formed from the DNA sequence found in human genomes. This image is based on an x-ray crystal structure of a G-quadruplex formed from ...

The direct observation and quantification of G-quadruplex structures formed from DNA in human cells during the cell cycle demonstrate the biological importance of these structures and point towards ...

DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...

Transform how we determine biomolecular structures. This PhD develops generative AI tools that use minimal NMR data to rapidly predict 3D G-quadruplex DNA/RNA structures – a major leap beyond ...

G-quadruplexes (G4s) are non-canonical structures formed by guanine-rich nucleic acids, increasingly implicated in transcriptional control, replication dynamics and genome stability at telomeres and ...

The world’s most famous molecule – the DNA double helix – sometimes doubles up again. Researchers have now found this quadruple-stranded form in healthy human cells for the first time. Four-stranded ...

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