Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta ...

What differentiates proteins from other molecules and materials is that their properties are encoded in their amino-acid sequences, which prescribe relationships between structure and function. A ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...

Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing question: Could a single molecule switch between two different roles like a ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics. Many ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structure of protein kinase C beta ...

In the ERC project HelixMold, a team from TU Graz developed a method for the computer-based design of artificial proteins, with a focus on custom biocatalysts for pharmaceutical applications or the ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

Over the millennia, viruses have become excellent manipulators of biology. But there’s a lot that scientists don’t know about how viruses work, in part because they have relatively little insight into ...