There is currently no cure for prion disease, and the new approach could be an important step towards treatments that prevent ...

The prion disease that causes deer, elk and other cervids to waste away could someday jump to humans, but many hunters are ...

this has been termed a 'subversion of function'. If so, PrP C contributes to neurotoxicity in prion disease but by uncertain mechnisms.

Viralgen and two labs based in the Broad Institute of MIT (Massachusetts Institute of Technology) and Harvard University have ...

Chronic Wasting Disease is a fatal neurological disease affecting hoofed animals. Idaho just received its second case from a ...

Doxycycline has also been shown to prevent the formation of misfolded proteins in another prion disease, called Creutzfeldt-Jakob disease, helping patients live twice as long as those who didn't ...

A lipid anchor on nerve cell membranes stabilizes prion proteins (PrPC) and prevents their pathological aggregation into forms linked to prion diseases.

A neurodegenerative prion disease, FFI is caused by a mutation ... The symptoms worsen with the passage of time and at one point, the patient cannot sleep at all. These patients also experience ...

preventing harmful aggregation linked to prion diseases. Their in vitro and cell culture models show how these anchors inhibit clumping, offering potential pathways for treatments targeting the ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative ...