Cholesterol, a fat-like substance in the body best known for its role in cardiovascular health, also plays a key role in how ...

Cells have surface receptors that couple with proteins and other molecules to initiate or inhibit certain behaviors. Typically, the number of these receptors increases as the cell matures, but ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

A Northwestern Medicine study has revealed a key mechanism underlying the development of motor neuron diseases, offering new insights into potential treatment options, according to a study published ...

The dopaminergic system has key roles in human physiology and is implicated in a broad range of neurological and neuropsychiatric conditions that are increasingly investigated using induced ...

Researchers were able to restore the function of neurons linked to cognitive function and information processing in mice that ...

UCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical window of prenatal brain development, finding that the condition alters the ...

Dopaminergic neurons arise from progenitor cells in the ventral midbrain under the coordinated influence of morphogens such as Sonic Hedgehog, Wnt and FGF, and the action of transcription factors ...