A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have ...

BRCA1 and BRCA2 genes play a crucial role in repairing damaged DNA. Mutations in BRCA1 and BRCA2 substantially increase the likelihood of breast and ovarian cancer, respectively. This new research ...

They also found that breast cancer cells that lose components of the complex that protects DNA from unnecessary DNA end cuts become resistant to chemotherapy drugs such as PARP inhibitors.

This mechanism is activated in the drug-resistant cancer cells. Consequently, the anticancer drug cannot reach the nucleus, where the target genome DNA exits. In contrast, polymeric micelles taken ...

UCLA researchers identified a new strain of drug-resistant bacteria in a study published ... Stewardship Program at UCLA Health, said multiple factors contribute to the problem.

expression inhibitor, APD-94, designed as an agent that could potentially overcome drug resistance in patients with colorectal cancer.

RICHMOND - A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib—an FDA ...