Did you ever wonder why all of a sudden someone develops a neurodegenerative disorder, heart disease, an autoimmune condition or even… cancer? Did it just drop down out of the sky and land on their ...
Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information is expressed that is indeed needed in this tissue. Now, for ...
Genetics is the study of heritable changes in gene activity or function due to the direct alteration of the DNA sequence. Such alterations include point mutations, deletions, insertions, and ...
In some people who carry a repeat expansion in the C9ORF72 gene, methylation of the gene promoter shuts down its transcription. This offers a modicum of protection against amyotrophic lateral ...
In the intricate landscape of human biochemistry, few processes wield as much influence over overall health as methylation. This fundamental cellular mechanism, involving the transfer of methyl groups ...
A review published in the journal Molecular Biomedicine provides a comprehensive overview of the METTL family, a group of methyltransferase-like proteins crucial for cellular function. METTL family ...
The metabolic syndrome, a major risk factor for type 2 diabetes and cardiovascular disease, is a cluster of metabolic abnormalities including obesity, insulin resistance, hypertension and dyslipidemia ...