Spliceosomal introns are noncoding DNA sequences located between exons in many eukaryotic protein-coding genes. Most are removed post-transcriptionally by RNA splicing and do not encode proteins, but ...

A genome-wide study identifies 9,814 poison exons in the human genome and shows that hundreds are brain-specific, linking their mis-splicing to neurological disorders such as Leigh syndrome.

A new study proves that a type of genetic element called 'introners' are the mechanism by which many introns spread within and between species, also providing evidence of eight instances in which ...

While working on a COVID-19-related project during the lockdown, Kärt Tomberg, PhD, found herself thinking about introns. She was part of a team working on the spike protein used in vaccines. Her task ...

Although the participation of spliceosomes is almost always required for intron removal, a few types of genes have self-splicing RNA introns. The RNA transcript of such a gene can carry out the entire ...

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders. The more complex the trait, the more of those differences ...