Two-step nanocage: Individual enzymes (orange and green) are first attached to half-cage structures. Half cages are then assembled into full cages, where reactants are brought into close proximity.

How an enzyme activates its substrate for turnover is fundamental for catalysis but incompletely understood on a structural level. With redox enzymes one typically analyses structures of ...

CHANGES of volume accompanying enzyme hydrolysis have been utilised by Sreenivasaya and Sastry 1 to follow the kinetics of enzyme action by means of the dilatometer. The procedure employed in the ...

The enzyme accelerates this reaction by 10 17 times, simply by positioning negative and positive charges in the active centre. Since the substrate contains a negatively charged group that is split off ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

Enzymes are proteins that catalyze chemical reactions in living organisms. They are widely applied in industries such as food ...

Real-time measurement of the initial stage of an enzyme–substrate reaction is essential for reproducible enzyme kinetics data. Automated direct-flow injection systems couple with various detection and ...

Contrary to what previously thought, enzymes move towards areas with less substrate. They display such behavior despite not having any thinking or sensing capabilities. Contrary to what previously ...

It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...