Extract: The bilirubin-UDP-glucuronyl transferase (BGT) activity in liver of newborn rats was measured to determine if unconjugated bilirubin could be the trigger substance of glucuronyl transferase ...
Data from two preclinical studies, one involving a mouse model of inflammatory bowel disease 1 and the other a mouse model of pancreatitis, 2 support the therapeutic effects of administrations of ...
Patients with the Crigler–Najjar syndrome lack the enzyme uridine diphosphoglucuronate glucuronosyltransferase 1A1 (UGT1A1), the absence of which leads to severe unconjugated hyperbilirubinemia that ...
“Our lectins are lyophilized or liquid formats with detailed storage protocols to ensure stability and quality,” said the business development manager at Amerigo Scientific. “By offering conjugated ...
(A) ABC transporters: The normal functioning of ABCG8/ABCG5, ABCB4, and ABCB11 enables the transport of cholesterol, bile acids, and lipids into bile (left). Mutations in any of these result in ...
Crigler-Najjar syndrome (CNS) and Gilbert syndrome (GS) are rare autosomal recessive disorders causing unconjugated hyperbilirubinemia due to reduced ...
“By offering conjugated and unconjugated lectins, we empower researchers to dissect carbohydrate-driven processes in cancer, infection, and genetic disorders—with speed and reproducibility.” About ...