The alternative text for this image may have been generated using AI. Discovering active dendrimers by combinatorial split-and-mix synthesis and screening. Solid-phase peptide synthesis can be ...
Gene sequences for targets that have been identified by genomics approaches are cloned and expressed as target proteins that are suitable for screening with a probe library of small, drug-like ...
Mario Geysen's combinatorial library, circa 1984. Credit: Courtesy of Terry Sharrer" />Mario Geysen's combinatorial library, circa 1984. Credit: Courtesy of Terry Sharrer In the early 1980s, Mario ...
The process of selecting and blending genes to create artificial networks -- synthetic biology -- holds promise for many applications. But developing artificial networks takes time and is often ...
SAN DIEGO--(BUSINESS WIRE)-- Ligand Pharmaceuticals Incorporated (NASDAQ: LGND) today announced that it has agreed to divest and sell its combinatorial chemical library and associated proprietary ...
AMSBIO is a leading supplier of innovative tools for growing cells in a physiologically relevant manner. A unique Extracellular Matrix (ECM) Mimetic Library for engineering surfaces to direct receptor ...
It's the new mix and match. In the computer industry, programmers refer to modularity--the ability to shuffle different sections of computer code to create new software. In the life sciences, the ...
Proteins with desirable properties are often identified by screening libraries of related gene sequences. Successful applications include antibody engineering, vaccine development, and biocatalyst ...
The previous article in this series, From Conventional Mutagenesis to Complex, Rationally Designed Mutant Libraries, described how conventional site-directed mutagenesis methods have been improved to ...
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