The Carolina Panthers face the San Francisco 49ers on Monday, Nov. 24, 2025 at Levi’s Stadium in Santa Clara, California.

Both teams are fighting for playoff positioning as they meet by the Bay on Monday night. On Monday, Nov. 24, Week 12 of the NFL season will wrap up at Levi’s Stadium as the San Francisco 49ers (7-4) face the Carolina Panthers (6-5).

The New Orleans Saints and Carolina Panthers meet for the 56th time when the 1-1 Saints face the 0-2 Panthers in Carolina this afternoon. New Orleans is coming off a 20-10 home loss to Tampa Bay after an improbable comeback to pull out opening week at Atlanta.

In the second half, Purdy and Co. settled down, extending their lead with an 80-yard touchdown drive in the early stages of the third quarter. Christian McCaffrey was the one to find the end zone at that juncture, scoring from 12 yards out against his former team as he squared off against them for the first time since being traded in 2022.

In his first game against his former team, McCaffrey had 142 scrimmage yards and a touchdown as the 49ers won 20-9.