Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

Drugs originally designed to treat diabetes and obesity are reshaping medicine in unforeseen ways. Their impact on public health is really unprecedented in modern times, perhaps only upstaged by ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...

When Robert F. Kennedy Jr., the U.S. Secretary of Health and Human Services, was reportedly spotted using a nicotine pouch during his Senate confirmation hearing, it sparked a firestorm of curiosity.

A doctor has issued a warning to vape users about a terrifying side effect which is most common among users under the age of 25. Vaping was first introduced as a healthier alternative to smoking, as ...