Inside our bones, an extraordinary process is taking place every moment of every day. Deep within the soft tissue known as bone marrow, the body continuously produces millions of new blood cells.

Mesenchymal stromal/stem cells (MSCs) are multipotent cells which have the ability to differentiate into multiple cell types, including chondrocytes, osteoblasts, adipocytes, and muscle cells [1].

Bone is a vital organ that is constantly remodeled throughout the lifetime 1. Bone consists of cortical bone that surrounds a central bone marrow cavity and trabecular bone that traverses a bone ...

Bone marrow fills the cavities in your bones and produces blood cells. Red blood cells carry oxygen, white blood cells fight germs, and platelets help blood clot. Bone marrow disorders include ...

While research has uncovered many details about how blood cells function within bone marrow, the work of other cells existing in that space remained a relative mystery. Now, researchers from the ...

EMBL scientists discovered self-sustaining inflammatory circuits in the bone marrow stem cell microenvironment that precede blood cancers. The illustration shows cancer cells against a background of ...

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells. This vital function is often disrupted in ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

MPNs involve overproduction of blood cells, while MDS results in poorly formed cells, affecting blood cell function and counts. Diagnosis requires blood tests, bone marrow biopsy, and genetic testing ...

A bone marrow transplant, or stem cell transplant, places blood stem cells back into the body. The transplant replaces cells that cancer or treatments have destroyed. People may have a bone marrow ...