In 1907, Aloysius "Alois" Alzheimer presented a rare case of dementia in a 51-year-old woman. This "presenile dementia" (younger than 60) was thought distinct enough from "senile dementia" (older than ...

At the turn of the 20th century, Dr. Alois Alzheimer noticed peculiar changes in a freshly removed brain. The brain had belonged to a 50-year-old woman who gradually lost her memory and struggled with ...

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid‐beta (amyloid) plaques and tau protein tangles.

When German psychiatrist Alois Alzheimer made the post-mortem discovery of amyloid plaques and neurofibrillary tangles in the early 1900s, he birthed the discovery of a cruel and insidious disorder.

In 1901, the Frankfurt Asylum had among its many anonymous patients a woman who left her name to posterity. Her name was Auguste Deter, and she was in her early 50s. She was unaware of the historical ...

Nature Milestones are editorially independent, produced with financial support from third parties. About this content. Alzheimer’s disease is the most common form of dementia, affecting more than 50 ...