San Francisco coach Kyle Shanahan explained how his wife changed his coaching practices after the success of 49ers backup quarterback Mac Jones.

The San Francisco 49ers will meet the Arizona Cardinals on Sunday for the second time this year, but they might be without a starter.

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The San Francisco 49ers had a rough outing in Week 10, falling to the Los Angeles Rams 42-26. That put San Francisco at a 6-4 record, dropping them to third place in the NFC West, and outside of the playoff picture as a whole.

Leaders from University of the Pacific and the San Francisco 49ers came together on Friday to announce a multiyear partnership to expand access to higher education.

For the Cardinals, all of Marvin Harrison Jr. (illness), Will Johnson (back/hip), Dadrion Taylor-Demerson (ankle), Jonah Williams (shoulder), Mack Wilson (ribs), Baron Browning (concussion) and Hayden Conner (knee) are out.

The Arizona Cardinals have a lengthy injury report ahead of Week 11, with seven players officially ruled out against the San Francisco 49ers.

Kyle Shanahan joined Matt Maiocco on "49ers Game Plan" to detail San Francisco's "open-door policy" for constructing offensive game plans.